Abstract Of The WEEK

To submit an "Abstract Of The Week" to the NPTA, please click here to fill out the form. If selected, your entry will be pubished on the NPTA blog. 

Many more abstracts can be found at PubMed or by clicking here. 


Resistance strength training exercise in children with spinal muscular atrophy.



Preliminary evidence in adults with spinal muscular atrophy (SMA) and in SMA animal models suggests exercise has potential benefits in improving or stabilizing muscle strength and motor function.


We evaluated feasibility, safety, and effects on strength and motor function of a home-based, supervised progressive resistance strength training exercise program in children with SMA types II and III. Up to 14 bilateral proximal muscles were exercised 3 times weekly for 12 weeks.


Nine children with SMA, aged 10.4 ± 3.8 years, completed the resistance training exercise program. Ninety percent of visits occurred per protocol. Training sessions were pain-free (99.8%), and no study-related adverse events occurred. Trends in improved strength and motor function were observed.


A 12-week supervised, home-based, 3-day/week progressive resistance training exercise program is feasible, safe, and well tolerated in children with SMA. These findings can inform future studies of exercise in SMA.


home-based exercise program; neuromuscular disorder; progressive resistance training exercise; spinal muscular atrophy; strength training exercise

PMID: 25597614
PMCID: PMC4506899
DOI: 10.1002/mus.24568


To read the full abstract, click here.

This Abstract was submitted by Landon Pillsbury, PT, DPT - Creighton University Pediatric PT Resident

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